3tti
Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitorCrystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor
About this StructureAbout this Structure
3tti is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Plantevin Krenitsky V, Nadolny L, Delgado M, Ayala L, Clareen SS, Hilgraf R, Albers R, Hegde S, D'Sidocky N, Sapienza J, Wright J, McCarrick M, Bahmanyar S, Chamberlain P, Delker SL, Muir J, Giegel D, Xu L, Celeridad M, Lachowitzer J, Bennett B, Moghaddam M, Khatsenko O, Katz J, Fan R, Bai A, Tang Y, Shirley MA, Benish B, Bodine T, Blease K, Raymon H, Cathers BE, Satoh Y. Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1433-8. Epub 2011 Dec 10. PMID:22244937 doi:10.1016/j.bmcl.2011.12.027