Colicin Ia is a type of Colicin, a bacteriocin made by E. Coli which acts against other nearby E. Coli to kill them by forming a pore in the membrane, leading to depolarisation of the membrane which kills the cell.

Synthesis and releaseSynthesis and release

Mechanism of uptakeMechanism of uptake

The N terminus is responsible for the translocation of colicin Ia across the membrane of the targeted cell. There is much flexibility on this region[1]

Killing ActivitiesKilling Activities

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Gemma McGoldrick, Alexander Berchansky, Michal Harel