3ekk

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Template:STRUCTURE 3ekk

File:3ekk.png

Insulin receptor kinase complexed with an inhibitorInsulin receptor kinase complexed with an inhibitor

Template:ABSTRACT PUBMED 19056263

About this StructureAbout this Structure

3EKK is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8

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OCA

[1] Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8

[xtra 1]