3krr
Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitorCrystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor
About this StructureAbout this Structure
3KRR is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Baffert F, Regnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chene P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, Ledieu D, Nolan L, Ruetz S, Trappe J, Vangrevelinghe E, Wartmann M, Wyder L, Hofmann F, Radimerski T. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. Mol Cancer Ther. 2010 Jul;9(7):1945-55. Epub 2010 Jun 29. PMID:20587663 doi:10.1158/1535-7163.MCT-10-0053
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