7ewh

Crystal structure of human PHGDH in complex with HomoharringtonineCrystal structure of human PHGDH in complex with Homoharringtonine

Structural highlights 7ewh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.99Å Ligands: Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SERA_HUMAN Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815. It is characterized by congenital microcephaly, psychomotor retardation, and seizures. Function SERA_HUMAN See Also Phosphoglycerate dehydrogenase

spinqualitylabelsall models 7ewh, resolution 2.99Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image