5tmb

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Crystal structure of Os79 from O. sativa in complex with UDP.Crystal structure of Os79 from O. sativa in complex with UDP.

Structural highlights

5tmb is a 1 chain structure with sequence from Oryza sativa Japonica Group. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.34Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UGT79_ORYSJ Involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-D-glucose to the hydroxyl group at C-3, forming deoxynivalenol-3-O-beta-D-glucoside.[1] [2]

See Also

References

  1. ↑ Michlmayr H, Malachova A, Varga E, Kleinova J, Lemmens M, Newmister S, Rayment I, Berthiller F, Adam G. Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-beta-D-glucoside. Toxins (Basel). 2015 Jul 21;7(7):2685-700. doi: 10.3390/toxins7072685. PMID:26197338 doi:http://dx.doi.org/10.3390/toxins7072685
  2. ↑ Wetterhorn KM, Newmister SA, Caniza RK, Busman M, McCormick SP, Berthiller F, Adam G, Rayment I. Crystal structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase involved in the detoxification of deoxynivalenol. Biochemistry. 2016 Oct 7. PMID:27715009 doi:http://dx.doi.org/10.1021/acs.biochem.6b00709

5tmb, resolution 2.34Å

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OCA
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