5jp4

Crystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDCCrystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDC

Structural highlights 5jp4 is a 2 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.043Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DCP1_SCHPO Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body.

spinqualitylabelsall models 5jp4, resolution 2.04Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image