3lsv
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Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter ViolaceusStructure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus
Structural highlights
FunctionGLIC_GLOVI Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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