3jrf

Crystal structure of Fis bound to 27 bp DNA F27 containing a C/G at centerCrystal structure of Fis bound to 27 bp DNA F27 containing a C/G at center

Structural highlights

3jrf is a 4 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.05Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FIS_ECOLI Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559
↑ Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178

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OCA

[1] Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559

[2] Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178

[1]

[2]

3jrf

Crystal structure of Fis bound to 27 bp DNA F27 containing a C/G at centerCrystal structure of Fis bound to 27 bp DNA F27 containing a C/G at center

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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3jrf

Crystal structure of Fis bound to 27 bp DNA F27 containing a C/G at centerCrystal structure of Fis bound to 27 bp DNA F27 containing a C/G at center

Structural highlights

Function

Evolutionary Conservation

See Also

References

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