3gd6

Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphateCrystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate

Structural highlights

3gd6 is a 1 chain structure with sequence from Oceanobacillus iheyensis HTE831. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.6Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GALRD_OCEIH Catalyzes the regioselective dehydration of galactarate into 2-keto-D-threo-4,5-dihydroxyadipate ((2S,3R)-dihydroxy-5-oxohexanedioate). Is not active on other acid sugars.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Rakus JF, Kalyanaraman C, Fedorov AA, Fedorov EV, Mills-Groninger FP, Toro R, Bonanno J, Bain K, Sauder JM, Burley SK, Almo SC, Jacobson MP, Gerlt JA. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry. 2009 Dec 8;48(48):11546-58. PMID:19883118 doi:10.1021/bi901731c

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OCA

[1] Rakus JF, Kalyanaraman C, Fedorov AA, Fedorov EV, Mills-Groninger FP, Toro R, Bonanno J, Bain K, Sauder JM, Burley SK, Almo SC, Jacobson MP, Gerlt JA. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry. 2009 Dec 8;48(48):11546-58. PMID:19883118 doi:10.1021/bi901731c

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3gd6

Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphateCrystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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3gd6

Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphateCrystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate

Structural highlights

Function

Evolutionary Conservation

See Also

References

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