3fxq

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Crystal structure of the LysR-type transcriptional regulator TsaRCrystal structure of the LysR-type transcriptional regulator TsaR

Structural highlights

3fxq is a 2 chain structure with sequence from Comamonas testosteroni. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TSAR_COMTE Regulates expression of the tsaMBCD1 operon and of tsaT in response to p-toluenesulfonate (TSA). Acts by binding directly to the promoter region. Binding to the tsa promoter depends on TSA concentration.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Tralau T, Mampel J, Cook AM, Ruff J. Characterization of TsaR, an oxygen-sensitive LysR-type regulator for the degradation of p-toluenesulfonate in Comamonas testosteroni T-2. Appl Environ Microbiol. 2003 Apr;69(4):2298-305. PMID:12676713 doi:10.1128/AEM.69.4.2298-2305.2003
  2. ↑ Tralau T, Cook AM, Ruff J. An additional regulator, TsaQ, is involved with TsaR in regulation of transport during the degradation of p-toluenesulfonate in Comamonas testosteroni T-2. Arch Microbiol. 2003 Nov;180(5):319-26. PMID:13680097 doi:10.1007/s00203-003-0594-8

3fxq, resolution 1.85Å

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OCA
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