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Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritimaCrystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima
Structural highlights
FunctionIOLG_THEMA Catalyzes the NAD(+)-dependent oxidation of myo-inositol (MI) to 2-keto-myo-inositol (scyllo-inosose), and thus probably functions in a myo-inositol degradation pathway together with IolM, IolN and IolO. Has no activity with scyllo-inositol and much reduced activity (78-fold lower catalytic efficiency) with 1D-chiro-inositol.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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