2hrb

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Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+

Structural highlights

2hrb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CBR3_HUMAN Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Miura T, Nishinaka T, Terada T. Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1. Mol Cell Biochem. 2008 Aug;315(1-2):113-21. doi: 10.1007/s11010-008-9794-5. Epub , 2008 May 21. PMID:18493841 doi:http://dx.doi.org/10.1007/s11010-008-9794-5

2hrb, resolution 1.90Å

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OCA
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