2he3
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Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
Structural highlights
FunctionGPX2_HUMAN Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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