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Crystal Structure of Holliday Junction Resolvase ST1444Crystal Structure of Holliday Junction Resolvase ST1444
Structural highlights
FunctionHJC_SULTO A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm).[HAMAP-Rule:MF_01490][1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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