2dt9

Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavusCrystal structure of the regulatory subunit of aspartate kinase from Thermus flavus

Structural highlights

2dt9 is a 2 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.15Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AK_THETH Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Nishiyama M, Kukimoto M, Beppu T, Horinouchi S. An operon encoding aspartokinase and purine phosphoribosyltransferase in Thermus flavus. Microbiology. 1995 May;141 ( Pt 5):1211-9. PMID:7773416
↑ Kobashi N, Nishiyama M, Tanokura M. Kinetic and mutation analyses of aspartate kinase from Thermus flavus. J Biosci Bioeng. 1999;87(6):739-45. PMID:16232547

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OCA

[1] Nishiyama M, Kukimoto M, Beppu T, Horinouchi S. An operon encoding aspartokinase and purine phosphoribosyltransferase in Thermus flavus. Microbiology. 1995 May;141 ( Pt 5):1211-9. PMID:7773416

[2] Kobashi N, Nishiyama M, Tanokura M. Kinetic and mutation analyses of aspartate kinase from Thermus flavus. J Biosci Bioeng. 1999;87(6):739-45. PMID:16232547

[1]

[2]

2dt9

Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavusCrystal structure of the regulatory subunit of aspartate kinase from Thermus flavus

Structural highlights

Function

Evolutionary Conservation

References

Contents

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2dt9

Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavusCrystal structure of the regulatory subunit of aspartate kinase from Thermus flavus

Structural highlights

Function

Evolutionary Conservation

References

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Navigation menu

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