1z08
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GppNHp-Bound Rab21 Q53G mutant GTPaseGppNHp-Bound Rab21 Q53G mutant GTPase
Structural highlights
FunctionRAB21_HUMAN Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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