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Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase IIICrystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III
Structural highlights
FunctionDPO3X_ECOLI DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Isoform tau: serves as a scaffold to help in the dimerization of the core complex. Isoform gamma: seems to interact with the delta subunit. to transfer the beta subunit on the DNA. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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