2bim
HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-N268D-R273HHUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-N268D-R273H
Template:ABSTRACT PUBMED 15703170
About this StructureAbout this Structure
2BIM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR. Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations. J Biol Chem. 2005 Apr 22;280(16):16030-7. Epub 2005 Feb 9. PMID:15703170 doi:http://dx.doi.org/10.1074/jbc.M500179200
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Fersht, A R.
- Joerger, A C.
- 3d-structure
- Activator
- Anti-oncogene
- Apoptosis
- Disease mutation
- Dna-binding
- Dna-binding protein
- Li-fraumeni syndrome
- Nuclear protein
- P53 dna-binding domain
- Phosphorylation
- Polymorphism
- Second-site suppressor mutation
- Superstable mutant
- Transcription regulation
- Transferase
- Tumor suppressor