3b2v
Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
DiseaseDisease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this StructureAbout this Structure
3B2V is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Feb 16 14:30:43 2009
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OCACategories:
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- Homo sapiens
- Receptor protein-tyrosine kinase
- Ferguson, K M.
- Kussie, P.
- Li, S.
- Alternative splicing
- Anti-oncogene
- Antigen:antibody complex
- Antitumor
- Atp-binding
- Cell cycle
- Cell surface receptor
- Disease mutation
- Drug
- Fab fragment
- Glycoprotein
- Immune system/transferase complex
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Secreted
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Ubl conjugation