3faa
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitorCrystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Template:ABSTRACT PUBMED 19135364
DiseaseDisease
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this StructureAbout this Structure
3FAA is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
2-Aminoimidazoles inhibitors of TGF-beta receptor 1., Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC, Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 [[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
Page seeded by OCA on Mon Feb 9 20:19:31 2009
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein serine/threonine kinase
- Single protein
- Atp-binding
- Craniosynostosis
- Disease mutation
- Glycoprotein
- Kinase
- Magnesium
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Protein-inhibitor complex
- Receptor
- Serine/threonine-protein kinase
- Structure-based drug design
- Tgfbeta
- Transferase
- Transmembrane