2ld5

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Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNASolution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA

Structural highlights

2ld5 is a 3 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

HXA13_MOUSE Defects in Hoxa13 are the cause of hypodactyly (Hd), a condition characterized by profound deficiency of digital arch structures.

Function

HXA13_MOUSE Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity).

See Also

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