1lf7
Crystal Structure of Human Complement Protein C8gamma at 1.2 A ResolutionCrystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution
Structural highlights
FunctionCO8G_HUMAN C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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