Sandbox testing Sn2 for Veronika

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SN2 reaction is a basic reaction type in organic chemistry. The letter SN stands for nulceophilic Substitution, the number 2 stands for bimolecular, with both reactions partners are involved in the reaction rate determining step. It also exists an SN1 reaction; here, only one reaction partner is involved in this step. On the other side, SN2 reactions are characterized by exchanging substituents. The substituent that leaves the molecule is called leaving group. Typically, alkanes with a substituent in primary position undergo SN2 reactions. In contrast to a SN1 reaction, no stable carbo cation can be formed, therefore, another way is taken. The SN2 by establishing a so called intermediate state, with both educts comeing close to each other. By this, the bond of the leaving group is partly broken, and the bond to the new group is partly formed. The formation of this intermediate state is the rate determining step of the reaction. In the , the bond of the leaving group is completely broken, and at the same time the bond to the new substituent is completely formed. The SN2 reaction has a very interesting stereochemistry inversion of the stereocenter with an animated example of the substitution of chloride and methanol shown. Please click on the buttons below to animate the reaction with different representations. Use the popup button to enlarge the view and the quality button to turn on anti-aliasing. Structural highlights This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image