3lpb

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3lpb.jpg

Template:STRUCTURE 3lpb

Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitorCrystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor

Template:ABSTRACT PUBMED 20231096

About this StructureAbout this Structure

3LPB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Pissot-Soldermann C, Gerspacher M, Furet P, Gaul C, Holzer P, McCarthy C, Radimerski T, Regnier CH, Baffert F, Drueckes P, Tavares GA, Vangrevelinghe E, Blasco F, Ottaviani G, Ossola F, Scesa J, Reetz J. Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2609-13. Epub 2010 Feb 19. PMID:20231096 doi:10.1016/j.bmcl.2010.02.056

Page seeded by OCA on Wed Apr 28 10:45:42 2010

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Pissot-Soldermann C, Gerspacher M, Furet P, Gaul C, Holzer P, McCarthy C, Radimerski T, Regnier CH, Baffert F, Drueckes P, Tavares GA, Vangrevelinghe E, Blasco F, Ottaviani G, Ossola F, Scesa J, Reetz J. Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2609-13. Epub 2010 Feb 19. PMID:20231096 doi:10.1016/j.bmcl.2010.02.056

[xtra 1]