Prolyl endopeptidases (PEPs) are a class of serine proteases known to have a role in the degradation of neuropeptides and peptide hormones. PEPs are large enzymes (75kDa) that cleave after proline residues in the peptide chain.
StructureStructure
β-Propeller Domainβ-Propeller Domain
Catalytic DomainCatalytic Domain
FunctionFunction
Binding MechanismBinding Mechanism
InhibitionInhibition
Pharmaceutical PossibilitiesPharmaceutical Possibilities
Celiac DiseaseCeliac Disease
Neurological DisordersNeurological Disorders
ReferencesReferences