2ano

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Template:STRUCTURE 2ano

File:2ano.png

Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17

Template:ABSTRACT PUBMED 17125251

About this StructureAbout this Structure

2ANO is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region., Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS, J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251

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