2dqt
High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analogHigh resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
About this StructureAbout this Structure
This structure supersedes the now removed PDB entry 1hyx. Full crystallographic information is available from OCA.
ReferenceReference
Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis., Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I, J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:17428500
Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization., Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A, Fujii I, J Mol Biol. 1997 Apr 18;267(5):1247-57. PMID:9150409
A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10757. PMID:7938025
A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6045-9. PMID:8016113
Prodrug activation via catalytic antibodies., Miyashita H, Karaki Y, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5337-40. PMID:8506382
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