1nql
Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.
Template:ABSTRACT PUBMED 12620237
DiseaseDisease
Known disease associated with this structure: Hypomagnesemia 4, renal OMIM:[131530]
About this StructureAbout this Structure
1NQL is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization., Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA, Mol Cell. 2003 Feb;11(2):507-17. PMID:12620237
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