2v22
REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORSREPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS
Template:ABSTRACT PUBMED 17051658
About this StructureAbout this Structure
2V22 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors., Andrews MJ, Kontopidis G, McInnes C, Plater A, Innes L, Cowan A, Jewsbury P, Fischer PM, Chembiochem. 2006 Dec;7(12):1909-15. PMID:17051658
Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design., Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM, Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568
Page seeded by OCA on Mon Jul 28 02:57:26 2008
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Protein complex
- Andrews, M J.
- Cowan, A.
- Fischer, P M.
- Innes, L.
- Jewsbury, P.
- Kontopidis, G.
- Mcinnes, C.
- Plater, A.
- Active
- Atp-binding
- Cdk2
- Cell cycle
- Cell division
- Cyclin
- Cyclin groove
- Inhibition
- Kinase
- Mitosis
- Nonpeptide
- Nucleotide-binding
- Phosphorylation
- Polymorphism
- Serine/threonine-protein kinase
- Transferase