1na7

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File:1na7.gif

Template:STRUCTURE 1na7

Crystal structure of the catalytic subunit of human protein kinase CK2


OverviewOverview

The three-dimensional crystal structure of the triple-point mutant of the catalytic subunit of human protein kinase CK2alpha has been determined at 2.4 A resolution. Microcrystals of mutant CK2 catalytic subunit were obtained by a protein-crystallization method based on thin-film nanotechnology. These microcrystals (of about 20 micro m in diameter) were used for diffraction data collection by means of the microfocus beamline at the ESRF synchrotron. A comparison between the human protein kinase CK2alpha and the corresponding enzyme from a lower organism (Zea mays) is made.

About this StructureAbout this Structure

1NA7 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2., Pechkova E, Zanotti G, Nicolini C, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2133-9. Epub 2003, Nov 27. PMID:14646071 Page seeded by OCA on Sat May 3 02:17:09 2008

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