1j5e
Structure of the Thermus thermophilus 30S Ribosomal Subunit
OverviewOverview
Genetic information encoded in messenger RNA is translated into protein by the ribosome, which is a large nucleoprotein complex comprising two subunits, denoted 30S and 50S in bacteria. Here we report the crystal structure of the 30S subunit from Thermus thermophilus, refined to 3 A resolution. The final atomic model rationalizes over four decades of biochemical data on the ribosome, and provides a wealth of information about RNA and protein structure, protein-RNA interactions and ribosome assembly. It is also a structural basis for analysis of the functions of the 30S subunit, such as decoding, and for understanding the action of antibiotics. The structure will facilitate the interpretation in molecular terms of lower resolution structural data on several functional states of the ribosome from electron microscopy and crystallography.
About this StructureAbout this Structure
1J5E is a Protein complex structure of sequences from Thermus thermophilus. This structure supersedes the now removed PDB entry 1fjf. Full crystallographic information is available from OCA.
ReferenceReference
Structure of the 30S ribosomal subunit., Wimberly BT, Brodersen DE, Clemons WM Jr, Morgan-Warren RJ, Carter AP, Vonrhein C, Hartsch T, Ramakrishnan V, Nature. 2000 Sep 21;407(6802):327-39. PMID:11014182 Page seeded by OCA on Fri May 2 20:49:45 2008