1g1x
STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA
OverviewOverview
The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.
About this StructureAbout this Structure
1G1X is a Protein complex structure of sequences from Thermus thermophilus. This structure supersedes the now removed PDB entry 1ekc. Full crystallographic information is available from OCA.
ReferenceReference
Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:10753109 Page seeded by OCA on Fri May 2 17:01:54 2008