8imx

Cryo-EM structure of GPI-T with a chimeric GPI-anchored proteinCryo-EM structure of GPI-T with a chimeric GPI-anchored protein

8imx is a 7 chain structure with sequence from Clavularia sp., Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 2.85Å
Ligands:	, , , , , , , , , , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

GFPL_CLASP ULBP2_HUMAN Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.^[1]

↑ Sutherland CL, Chalupny NJ, Schooley K, VandenBos T, Kubin M, Cosman D. UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J Immunol. 2002 Jan 15;168(2):671-9. PMID:11777960 doi:10.4049/jimmunol.168.2.671