Subtomogram average of the human Sec61-TRAP-OSTA-transloconSubtomogram average of the human Sec61-TRAP-OSTA-translocon

Structural highlights

8b6l is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

SSRD_HUMAN SSR4-CDG. The disease is caused by variants affecting the gene represented in this entry.

Function

SSRD_HUMAN TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8b6l, resolution 7.60Å

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OCA