8egx

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Complex of Fat4(EC1-4) bound to Dchs1(EC1-4)Complex of Fat4(EC1-4) bound to Dchs1(EC1-4)

Structural highlights

8egx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.688Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

FAT4_HUMAN Hennekam syndrome;Cerebrofacioarticular syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.

Function

FAT4_HUMAN Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity).

8egx, resolution 3.69Å

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OCA