7azd

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DNA polymerase sliding clamp from Escherichia coli with peptide 20 boundDNA polymerase sliding clamp from Escherichia coli with peptide 20 bound

Structural highlights

7azd is a 8 chain structure with sequence from Escherichia coli 2-427-07_S4_C3 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.19Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPO3B_ECOLI DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

See Also

7azd, resolution 2.19Å

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