1r9f

Crystal structure of p19 complexed with 19-bp small interfering RNACrystal structure of p19 complexed with 19-bp small interfering RNA

Structural highlights 1r9f is a 3 chain structure with sequence from Tomato bushy stunt virus. The February 2008 RCSB PDB Molecule of the Month feature on Small Interfering RNA by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.85Å Ligands: , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function P19_TBSVC Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Binds to short interfering RNAs (siRNAs) with high affinity. Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Flock house virus protein B2 P19 complexed with 19-bp small interfering RNA RNA silencing suppressor Suppression of RNA Silencing by Viruses Tomato aspermy virus protein 2b Suppression of RNA Silencing

spinqualitylabelsall models 1r9f, resolution 1.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image