5tus

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Potent competitive inhibition of human ribonucleotide reductase by a novel non-nucleoside small moleculePotent competitive inhibition of human ribonucleotide reductase by a novel non-nucleoside small molecule

Structural highlights

5tus is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.66Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIR1_HUMAN Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

See Also

5tus, resolution 2.66Å

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