1we0

Crystal structure of peroxiredoxin (AhpC) from Amphibacillus xylanusCrystal structure of peroxiredoxin (AhpC) from Amphibacillus xylanus

Structural highlights

1we0 is a 10 chain structure with sequence from Amphibacillus xylanus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AHPC_AMPXN Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Niimura Y, Nishiyama Y, Saito D, Tsuji H, Hidaka M, Miyaji T, Watanabe T, Massey V. A hydrogen peroxide-forming NADH oxidase that functions as an alkyl hydroperoxide reductase in Amphibacillus xylanus. J Bacteriol. 2000 Sep;182(18):5046-51. PMID:10960086 doi:10.1128/JB.182.18.5046-5051.2000

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OCA

[1] Niimura Y, Nishiyama Y, Saito D, Tsuji H, Hidaka M, Miyaji T, Watanabe T, Massey V. A hydrogen peroxide-forming NADH oxidase that functions as an alkyl hydroperoxide reductase in Amphibacillus xylanus. J Bacteriol. 2000 Sep;182(18):5046-51. PMID:10960086 doi:10.1128/JB.182.18.5046-5051.2000

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