1j78

Crystallographic analysis of the human vitamin D binding proteinCrystallographic analysis of the human vitamin D binding protein

Structural highlights 1j78 is a 2 chain structure with sequence from Homo sapiens. The November 2012 RCSB PDB Molecule of the Month feature on Vitamin D Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2012_11. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.31Å Ligands: , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VTDB_HUMAN Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

spinqualitylabelsall models 1j78, resolution 2.31Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image