1bb6

LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOTRIOSELYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOTRIOSE

Structural highlights

1bb6 is a 1 chain structure with sequence from Oncorhynchus mykiss. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LYSC2_ONCMY Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has antibacterial activity against the Gram positive bacterium P.citreus. Has no antibacterial activity against the Gram negative bacteria E.coli and Y.ruckeri. Does not have hemolytic activity against trout erythrocytes.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Fernandes JM, Kemp GD, Smith VJ. Two novel muramidases from skin mucosa of rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol B Biochem Mol Biol. 2004 May;138(1):53-64. PMID:15142536 doi:http://dx.doi.org/10.1016/j.cbpc.2004.02.004

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Fernandes JM, Kemp GD, Smith VJ. Two novel muramidases from skin mucosa of rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol B Biochem Mol Biol. 2004 May;138(1):53-64. PMID:15142536 doi:http://dx.doi.org/10.1016/j.cbpc.2004.02.004

[1]