1wgq

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Solution Structure of the Pleckstrin Homology Domain of Mouse Ethanol Decreased 4 ProteinSolution Structure of the Pleckstrin Homology Domain of Mouse Ethanol Decreased 4 Protein

Structural highlights

1wgq is a 1 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:RIKEN cDNA 4933427A08 (LK3 transgenic mice)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[FGD6_MOUSE] May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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OCA