2htt

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Ruthenium Hexammine ion interactions with Z-DNARuthenium Hexammine ion interactions with Z-DNA

Structural highlights

2htt is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Publication Abstract from PubMed

The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.

Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Bharanidharan D, Thiyagarajan S, Gautham N. Hexammineruthenium(III) ion interactions with Z-DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080 doi:http://dx.doi.org/S1744309107047781

2htt, resolution 2.60Å

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