Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosusConserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus

Structural highlights

1xg7 is a 2 chain structure with sequence from Pyrfu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[AGOG_PYRFU] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates (By similarity).

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1xg7, resolution 1.88Å

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OCA