Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivativeCrystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative

Structural highlights

8b2a is a 2 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AROD_STAAB Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

8b2a, resolution 1.65Å

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OCA