4owp

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Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.

Structural highlights

4owp is a 2 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPN8_YEAST Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1]

See Also

References

  1. ↑ Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun;18(6):3149-62. PMID:9584156

4owp, resolution 2.35Å

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