3raj

Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7

Structural highlights

3raj is a 3 chain structure with sequence from Human and Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	CD38 (HUMAN)
Activity:	NAD(+) nucleosidase, with EC number 3.2.2.5
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

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OCA

3raj

Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7

Structural highlights

Function

See Also

Contents

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