7sum

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Crystal structure of human ligase I with nick duplexes containing cognate A:TCrystal structure of human ligase I with nick duplexes containing cognate A:T

Structural highlights

7sum is a 4 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DNLI1_HUMAN] DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

7sum, resolution 2.90Å

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OCA
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