6x10

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Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with haloperidolCrystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with haloperidol

Structural highlights

6x10 is a 1 chain structure with sequence from Myctu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:eis, Rv2416c, MTCY253.04 (MYCTU)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.[1]

References

  1. Wei J, Dahl JL, Moulder JW, Roberts EA, O'Gaora P, Young DB, Friedman RL. Identification of a Mycobacterium tuberculosis gene that enhances mycobacterial survival in macrophages. J Bacteriol. 2000 Jan;182(2):377-84. PMID:10629183

6x10, resolution 2.03Å

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